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1

Anti-neutrophil cytoplasmic antibodies directed against the bactericidal/permeability-increasing protein (BPI) in pediatric cystic fibrosis patients do not recognize N-terminal regions important for the anti-microbial and lipopolysaccharide-binding activity of BPI

Hendrik Schultz, Elena Csernok, Antje Schuster, Thomas S. Schmitz, Martin Ernst, Wolfgang L. Gross

Journal:

Pediatric Allergy and Immunology

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

2

Performance of a novel chemiluminescence assay for the detection of anti-pr3, anti-MPO and anti-GBM autoantibodies

Mahler, Michael, Seaman, Andrea, Csernok, Elena, Damoiseaux, Jan, Sinico, Renato A., Radice, Antonella, Cui, Zhao, Vizjak, Alenka, Burlingame, Rufus W.

Journal:

Year:

2012

Language:

english

File:

PDF, 52 KB

english, 2012

3

Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations

Langley, Gillian R., Adcock, Ian M., Busquet, François, Crofton, Kevin M., Csernok, Elena, Giese, Christoph, Heinonen, Tuula, Herrmann, Kathrin, Hofmann-Apitius, Martin, Landesmann, Brigitte, Marshall

Journal:

Drug Discovery Today

Year:

2016

Language:

english

File:

PDF, 779 KB

english, 2016

4

Labordiagnostik bei Kollagenosen und Vaskulitiden

Journal:

Arthritis und Rheuma

Year:

2019

Language:

german

File:

PDF, 639 KB

german, 2019

5

MONOCLONAL ANTIBODY WGM1 DIRECTED AGAINST PROTEINASE 3: AN IMMUNOHISTOCHEMICAL MARKER FOR NAPHTHOL ASD CHLOROACETATE

MATTHIAS G. BRAUN, ELENA CSERNOK, WIEBKE RÖGENER-SCHWARZ, WOLF-DIETER LUDWIG, HANS-KONRAD MÜLLER-HERMELINK, WOLFGANG L. GROSS, ALFRED C. FELLER

Journal:

Hematological Oncology

Year:

1996

Language:

english

File:

PDF, 1.58 MB

english, 1996

6

Localized Wegener's granulomatosis: predominance of CD26 and IFN-γ expression

Antje Müller, Andreas Trabandt, Katharina Gloeckner-Hofmann, Ulrike Seitzer, Elena Csernok, Ulf Schönermarck, Alfred C. Feller, Wolfgang L. Gross

Journal:

The Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

7

Churg-Strauss syndrome: Serum markers of lymphocyte activation and endothelial damage

Wilhelm H. Schmitt, Elena Csernok, Shigeto Kobayashi, Anja Klinkenborg, Eva Reinhold-Keller, Wolfgang L. Gross

Journal:

Arthritis & Rheumatism

Year:

1998

Language:

english

File:

PDF, 842 KB

english, 1998

8

Autoantibodies against granulocyte colony-stimulating factor in Felty's syndrome and neutropenic systemic lupus erythematosus

Bernhard Hellmich, Elena Csernok, Helmut Schatz, Wolfgang L. Gross, Armin Schnabel

Journal:

Arthritis & Rheumatism

Year:

2002

Language:

english

File:

PDF, 153 KB

english, 2002

9

Elevated serum levels of soluble interleukin-2 receptor in patients with Wegener's granulomatosis. Association with disease activity

Wilhelm H. Schmitt, Christoph Heesen, Elena Csernok, Annegret Rautmann, Wolfgang L. Gross

Journal:

Arthritis & Rheumatism

Year:

1992

Language:

english

File:

PDF, 770 KB

english, 1992

10

Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus

Armin Schnabel, Elena Csernok, David A. Isenberg, Christian Mrowka, Wolfgang L. Gross

Journal:

Arthritis & Rheumatism

Year:

1995

Language:

english

File:

PDF, 571 KB

english, 1995

11

Reply

Simo Nikkari, Raija Vainionpää, Paavo Toivanen, Wolfgang L. Gross, Nouhad Mistry, Elena Csernok, Bo Baslund, Allan Wiik, Wladimir Szpirt

Journal:

Arthritis & Rheumatism

Year:

1995

Language:

english

File:

PDF, 107 KB

english, 1995

12

Incidence and disease associations of a proteinase 3−antineutrophil cytoplasmic antibody idiotype (5/7 Id) whose antiidiotype inhibits proteinase 3−antineutrophil cytoplasmic antibody antigen binding activity

Hendryk P. Strunz, Elena Csernok, Wolfgang L. Gross

Journal:

Arthritis & Rheumatism

Year:

1997

Language:

english

File:

PDF, 852 KB

english, 1997

13

The PTPN22 620W allele is a risk factor for Wegener's granulomatosis

Peter Jagiello, Peer Aries, Larissa Arning, Sonja E. N. Wagenleiter, Elena Csernok, Bernhard Hellmich, Wolfgang L. Gross, Joerg T. Epplen

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 63 KB

english, 2005

14

Diagnostic value of standardized assays for anti-neutrophil cytoplasmic antibodies in idiopathic systemic vasculitis

Hagen, E Christiaan, Daha, Mohamed R, Hermans, Jo, Andrassy, Konrad, Csernok, Elena, Gaskin, Gillian, Lesavre, Phillippe, Lüdemann, Jens, Rasmussen, Niels, Sinico, R Alberto, Wiik, Allan, van der Woud

Journal:

Kidney International

Year:

1998

Language:

english

File:

PDF, 381 KB

english, 1998

15

On the Wegener granulomatosis associated region on chromosome 6p21.3

Paweł Szyld, Peter Jagiello, Elena Csernok, Wolfgang L Gross, Joerg T Epplen

Journal:

BMC Medical Genetics

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006

16

Association study with Wegener granulomatosis of the humanphospholipase Cγ2gene

Peter Jagiello, Stefan Wieczorek, Philipp Yu, Elena Csernok, Wolfgang L Gross, Joerg T Epplen

Journal:

Journal of Negative Results in BioMedicine

Year:

2005

Language:

english

File:

PDF, 776 KB

english, 2005

17

Bactericidal Permeability Increasing Protein (BPI)-ANCA markiert chronische entzündliche Darmerkrankungen und entzündliche hepatobiliäre Erkrankungen

Armin Schnabel, Elena Csernok, Hendrik Schultz, Markus Stoffel, Christian Herzberg, Stephan F. Carroll, Wolfgang L. Gross

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

1997

File:

PDF, 890 KB

1997

18

New genomic region for Wegener’s granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes

Peter Jagiello, Martin Gencik, Larissa Arning, Stefan Wieczorek, Erdmute Kunstmann, Elena Csernok, WolfgangL. Gross, JoergT. Epplen

Journal:

Year:

2004

Language:

english

File:

PDF, 303 KB

english, 2004

19

Pathways to ANCA Production: From Differentiation of Dendritic Cells by Proteinase 3 to B Lymphocyte Maturation in Wegener’s Granuloma

Elena Csernok, Frank Moosig, Wolgang L. Gross

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2008

Language:

english

File:

PDF, 135 KB

english, 2008

20

Twenty-eight years with antineutrophil cytoplasmic antibodies (ANCA): how to test for ANCA — evidence-based immunology?

Elena Csernok, Julia U. Holle

Journal:

Autoimmunity Highlights

Year:

2010

Language:

english

File:

PDF, 114 KB

english, 2010

21

Selective killing of B-cell hybridomas targeting proteinase 3, Wegener's autoantigen

Katrin S. Reiners, Hinrich P. Hansen, Anne Krüssmann, Gisela Schön, Elena Csernok, Wolfgang L. Gross, Andreas Engert, Elke Pogge Von Strandmann

Journal:

Year:

2004

Language:

english

File:

PDF, 212 KB

english, 2004

22

Interleukin-15 stimulates macrophages to activate CD4+ T cells: a role in the pathogenesis of rheumatoid arthritis?

René Rückert, Katja Brandt, Martin Ernst, Kathleen Marienfeld, Elena Csernok, Claudia Metzler, Vadim Budagian, Elena Bulanova, Ralf Paus, Silvia Bulfone-Paus

Journal:

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

23

Human Proteinase 3 (PR3) and Its Binding Molecules : Implications for Inflammatory and PR3-Related Autoimmune Responses

ANTJE MÜLLER, JAN VOSWINKEL, STEFAN GOTTSCHLICH, ELENA CSERNOK

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

24

Standardization of Autoimmune Diagnostics in Germany : Activities of the German Group in the European Autoimmune Standardization Initiative

ULRICH SACK, KARSTEN CONRAD, ELENA CSERNOK, INGRID FRANK, MICHAEL HAASS, THORSTEN KRIEGER, MICHAEL SEYFARTH, UDO SCHLOSSER, REINHOLD E. SCHMIDT, TORSTEN WITTE

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 53 KB

english, 2007

25

Determination of Primary Amino Acid Sequence and Unique Three-Dimensional Structure of WGH1, a Monoclonal Human IgM Antibody with Anti-PR3 Specificity

Jacquelyn A. Davis, Elisabeth Peen, Ralph C. Williams Jr., Shane Perkins, Christine C. Malone, Wayne T. McCormack, Elena Csernok, W.L. Gross, A.S. Kolaskar, Urmila Kulkarni-Kale

Journal:

Clinical Immunology and Immunopathology

Year:

1998

Language:

english

File:

PDF, 652 KB

english, 1998

26

Alterations in the phenotype of CMV-specific and total CD8+ T-cell populations in Wegener’s granulomatosis

Peter Lamprecht, Ana L. Vargas Cuero, Antje Muller, Elena Csernok, Jan Voswinkel, Matthias Maass, Werner Solbach, Wolfgang L. Gross, Paul Klenerman

Journal:

Cellular Immunology

Year:

2003

Language:

english

File:

PDF, 215 KB

english, 2003

27

Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis

Dorin Capraru, Antje Müller, Elena Csernok, Wolfgang L. Gross, Konstanze Holl-Ulrich, John Northfield, Paul Klenerman, Karen Herlyn, Julia Holle, Stefan Gottschlich, Jan Voswinkel, Thomas Spies, Ursul

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

28

Use of native and recombinant bactericidal/permeability-increasing proteins (BPI) as antigens for detection of BPI-ANCA

Hendrik Schultz, Elena Csernok, Thomas W Johnston, Christopher M Lockwood, Wolfgang L Gross

Journal:

Journal of Immunological Methods

Year:

1997

Language:

english

File:

PDF, 194 KB

english, 1997

29

Comparison of eight commercial kits for quantitation of antineutrophil cytoplasmic antibodies (ANCA)

Guochun Wang, Elena Csernok, Kirsten de Groot, Wolfgang L Gross

Journal:

Journal of Immunological Methods

Year:

1997

Language:

english

File:

PDF, 242 KB

english, 1997

30

Antineutrophil cytoplasmic autoantibodies, autoantigens, and systemic vasculitis

WOLFGANG L. Gross, ELENA Csernok, UDO Helmchen

Journal:

Year:

1995

Language:

english

File:

PDF, 3.74 MB

english, 1995

31

NEUTROPHILS SYNTHESIZE AND ACTIVATE TGFβ2

Christof H Szymkowiak, Elena Csernok, Dirk Reinhold, Ute Bank, Wolfgang L Gross, Jörn Kekow

Journal:

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

32

Expression of the Human Autoantigen of Wegener's Granulomatosis (PR3) in a Baculovirus Expression System

Christof H. Szymkowiak, Thomas W. Johnston, Elena Csernok, Wolfgang L. Gross

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 455 KB

english, 1996

33

'Classic' Anti-Neutrophil Cytoplasmic Autoantibodies (cANCA), 'Wegener's Autoantigen' and Their Immunopathogenic Role in Wegener's Granulomatosis

Wolfgang L. Gross, Elena Csernok, Brigitte K. Flesch

Journal:

Journal of Autoimmunity

Year:

1993

File:

PDF, 678 KB

1993

34

Vitronectin- and Fibronectin-containing Immune Complexes in Primary Systemic Vasculitis

Karen Maehnss, Jörg Kobarg, Wilhelm H Schmitt, Hinrich P Hansen, Hans Lange, Elena Csernok, Wolfgang L Gross, Hilmar Lemke

Journal:

Journal of Autoimmunity

Year:

2002

Language:

english

File:

PDF, 178 KB

english, 2002

35

Cartilage Destruction in Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Is Mediated by Human Fibroblasts after Transplantation into Immunodeficient Mice

Nina Kesel, Dorothee Köhler, Lena Herich, Martin Laudien, Konstanze Holl-Ulrich, Astrid Jüngel, Michel Neidhart, Steffen Gay, Renate E. Gay, Elena Csernok, Peter Lamprecht, Wolfgang L. Gross, Udo Schu

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 5.58 MB

english, 2012

36

Frequency of proteinase 3 (PR3)-specific autoreactive T cells determined by cytokine flow cytometry in Wegener's granulomatosis

Jolanta Winek, Antje Mueller, Elena Csernok, Wolfgang L Gross, Peter Lamprecht

Journal:

Journal of Autoimmunity

Year:

2004

Language:

english

File:

PDF, 299 KB

english, 2004

37

Low Fcγ receptor III and high granulocyte colony-stimulating factor serum levels correlate with the risk of infection in neutropenia due to Felty’s syndrome or systemic lupus erythematosus

Bernhard Hellmich, Elena Csernok, Masja de Haas, Albert E.G.K.R von dem Borne, Helmut Schatz, Wolfgang L Gross, Armin Schnabel

Journal:

The American Journal of Medicine

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

38

High Plasma Levels of the Soluble Form of CD30 Activation Molecule Reflect Disease Activity in Patients with Wegener's Granulomatosis

Guochun Wang, MD, Hinrich Hansen, PhD, Efstratios Tatsis, MD, Elena Csernok, PhD, Hilmar Lemke, PhD, Wolfgang L. Gross, MD

Journal:

The American Journal of Medicine

Year:

1997

Language:

english

File:

PDF, 230 KB

english, 1997

39

Peripheral Blood and Granuloma CD4+CD28− T Cells Are a Major Source of Interferon-γ and Tumor Necrosis Factor-α in Wegener’s Granulomatosis

Andras Komocsi, Peter Lamprecht, Elena Csernok, Antje Mueller, Konstanze Holl-Ulrich, Ulrike Seitzer, Frank Moosig, Armin Schnabel, Wolfgang Ludwig Gross

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 908 KB

english, 2002

40

Bactericidal/permeability-increasing protein for severe meningococcal sepsis

Hendrik Schultz, Elena Csernok, Wolfgang L Gross

Journal:

Year:

1998

Language:

english

File:

PDF, 45 KB

english, 1998

41

Differences in CCR5 expression on peripheral blood CD4+CD28− T-cells and in granulomatous lesions between localized and generalized Wegener’s granulomatosis

Peter Lamprecht, Hilke Bruhl, Anika Erdmann, Konstanze Holl-Ulrich, Elena Csernok, Ulrike Seitzer, Matthias Mack, Alfred C Feller, Eva Reinhold-Keller, Wolfgang L Gross, Antje Muller

Journal:

Clinical Immunology

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

42

Anti-neutrophil cytoplasmic antibodies and pathogenesis of small vessel vasculitides

Journal:

Autoimmunity Reviews

Year:

2003

Language:

english

File:

PDF, 84 KB

english, 2003

43

ANCA testing: the current stage and perspectives

Journal:

Clinical and Experimental Nephrology

Year:

2013

Language:

english

File:

PDF, 196 KB

english, 2013

44

Progranulin antibodies in autoimmune diseases

Thurner, Lorenz, Preuss, Klaus-Dieter, Fadle, Natalie, Regitz, Evi, Klemm, Philipp, Zaks, Marina, Kemele, Maria, Hasenfus, Andrea, Csernok, Elena, Gross, Wolfgang L., Pasquali, Jean-Louis, Martin, Thi

Journal:

Journal of Autoimmunity

Year:

2013

Language:

english

File:

PDF, 675 KB

english, 2013

45

Cytokine profiles in Wegener's granulomatosis: Predominance of type 1 (Th1) in the granulomatous inflammation

Elena Csernok, Andreas Trabandt, Antje Müller, Guchoan C. Wang, Frank Moosig, Jens Paulsen, Armin Schnabel, Wolfgang L. Gross

Journal:

Arthritis & Rheumatism

Year:

1999

Language:

english

File:

PDF, 186 KB

english, 1999

46

Genetic predisposition (NLRP3 V198M mutation) for IL-1–mediated inflammation in a patient with Schnitzler syndrome

Loock, Jan, Lamprecht, Peter, Timmann, Christian, Mrowietz, Ulrich, Csernok, Elena, Gross, Wolfgang L.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 275 KB

english, 2010

47

Autoantibody Detection Using Indirect Immunofluorescence on HEp-2 Cells

Sack, Ulrich, Conrad, Karsten, Csernok, Elena, Frank, Ingrid, Hiepe, Falk, Krieger, Thorsten, Kromminga, Arno, Von Landenberg, Philipp, Messer, Gerald, Witte, Torsten, Mierau, Rudolf

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 184 KB

english, 2009

48

Current understanding of the pathogenesis of granulomatosis with polyangiitis (Wegener’s)

Csernok, Elena, Gross, Wolfgang L

Journal:

Expert Review of Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

49

Heterogeneity of CD4 and CD8+memory T cells in localized and generalized Wegener's granulomatosis

Peter Lamprecht, Anika Erdmann, Antje Mueller, Elena Csernok…

Journal:

Arthritis Research & Therapy

Year:

2002

Language:

english

File:

PDF, 845 KB

english, 2002

50

PR3-ANCA: A promising biomarker for ulcerative colitis with extensive disease

Mahler, Michael, Bogdanos, Dimitrios P., Pavlidis, Polychronis, Fritzler, Marvin J., Csernok, Elena, Damoiseaux, Jan, Bentow, Chelsea, Shums, Zakera, Forbes, Alastair, Norman, Gary L.

Journal:

Clinica Chimica Acta

Year:

2013

Language:

english

File:

PDF, 767 KB

english, 2013

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